[email protected] (受疫情影响,东南亚目前只开放曼谷诊所)
全周 (9AM - 5PM)

我们和你在一起

Extra info thumb
  • 总部: 泰国曼谷市巴吞汪区仑披尼分区 普勒吉路齐隆巷5号.
  • [email protected]
ZINC FINGER PROTEIN 123, PSEUDOGENE; ZNF123P

ZINC FINGER PROTEIN 123, PSEUDOGENE; ZNF123P

Alternative titles; symbolsZINC FINGER PROTEIN 123; ZNF123HGNC Approved Gene Symbol: ZNF123PCytogenetic location: 11q23.1-q23.2 Genomic coordinates (GRCh38):...

Alternative titles; symbols

  • ZINC FINGER PROTEIN 123; ZNF123

HGNC Approved Gene Symbol: ZNF123P

Cytogenetic location: 11q23.1-q23.2 Genomic coordinates (GRCh38): 11:110,600,000-114,600,000

▼ Cloning and Expression
Saleh et al. (1992) isolated, characterized, and mapped zinc finger-encoding genes specific to human chromosome 11q to investigate their possible association in a molecular pathogenesis of diseases mapping to that area of the genome. They screened an arrayed chromosome 11q cosmid library using a degenerate oligonucleotide corresponding to the histidine/cysteine link consensus sequence of the Drosophila Kruppel zinc finger gene. Six putative zinc finger genes were isolated; 3 of these--ZNF123, ZNF125 (194632), and ZNF126 (194633)--were analyzed and shown to contain tandemly repeated zinc finger motifs of the C2-H2 class. All 3 novel genes were found to be expressed in normal adult human tissues, although the tissue-specific pattern expression differed markedly. The ZNF123 gene was found to be expressed as a 3.5-kb transcript exclusively in human liver.

▼ Mapping
Saleh et al. (1992) regionally mapped the ZNF123, ZNF125, and ZNF126 genes to chromosome 11 using fluorescence in situ suppression hybridization (FISSH) as described by Selleri et al. (1991). The clone referred to as HZF-2, relating to the gene symbolized ZNF126, mapped to 11q13.3-q13.4; the clones HZF-1 and HZF-3, identified with genes ZNF123 and ZNF125, respectively, mapped to 11q23.1-q23.2.

Tags: 11q23.1, 11q23.2

相关文章

ZINC FINGER PROTEIN 123, PSEUDOGENE; ZNF123P
RNA-BINDING MOTIF PROTEIN 7; RBM7

HGNC Approved Gene Symbol: RB...

ZINC FINGER PROTEIN 123, PSEUDOGENE; ZNF123P
胎盘表达的转录本 1,小鼠,同源物

赵等人。(2004)克隆了小鼠和猪 Plet1,并通过基因...

ZINC FINGER PROTEIN 123, PSEUDOGENE; ZNF123P
泛素特异性蛋白酶 28

泛素依赖性蛋白质降解途径对于细胞内蛋白质和肽的蛋白水解是必...

ZINC FINGER PROTEIN 123, PSEUDOGENE; ZNF123P
线粒体复合物 II 缺陷,3 型核

有证据表明线粒体复合物 II 缺陷核型 3 (MC2DN3...

ZINC FINGER PROTEIN 123, PSEUDOGENE; ZNF123P
多巴胺受体 D2

D2 多巴胺受体是一种 G 蛋白偶联受体,位于突触后多巴胺...

遇到问题了吗?