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RIGHT PULMONARY ARTERY, ANOMALOUS ORIGIN OF, FAMILIAL

RIGHT PULMONARY ARTERY, ANOMALOUS ORIGIN OF, FAMILIAL

Alternative titles; symbolsRIGHT PULMONARY ARTERY, ANOMALOUS ORIGIN OF, WITH VENTRICULAR SEPTAL DEFECT, PATENT FORAMEN OVALE, AND PATENT DUCTUS ARTERIOSUSARPA, F...

Alternative titles; symbols

  • RIGHT PULMONARY ARTERY, ANOMALOUS ORIGIN OF, WITH VENTRICULAR SEPTAL DEFECT, PATENT FORAMEN OVALE, AND PATENT DUCTUS ARTERIOSUS
  • ARPA, FAMILIAL

▼ Clinical Features
Vergara et al. (2006) reported a 10-day-old male infant in whom echocardiography showed anomalous origin of the right pulmonary artery (ARPA) from the ascending aorta, patent foramen ovale, a small subaortic ventricular septal defect, and patent ductus arteriosus. The left pulmonary artery originated from the pulmonary trunk but was stenotic at the origin. The patient's father had undergone cardiac catheterization at 7 months of age, which showed a large aortopulmonary window, patent foramen ovale, ventricular septal defect, and small patent ductus arteriosus. Vergara et al. (2006) also reported a second family that had a newborn male with echocardiographic diagnosis of ARPA without associated congenital heart disease and a newborn girl from another branch of the family with ARPA, patent ductus arteriosus, atrial septal defect, and aortic coarctation by echocardiography. None of the patients had any dysmorphic features, and neuropsychologic development was normal. No associated malformations were detected by cerebral and renal ultrasonography in the 3 infants.

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