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RAS-ASSOCIATED PROTEIN RAB30; RAB30

RAS-ASSOCIATED PROTEIN RAB30; RAB30

HGNC Approved Gene Symbol: RAB30Cytogenetic location: 11q14.1 Genomic coordinates (GRCh38): 11:82,973,132-83,071,896 (from NCBI)▼ Cloning and ExpressionChen ...

HGNC Approved Gene Symbol: RAB30

Cytogenetic location: 11q14.1 Genomic coordinates (GRCh38): 11:82,973,132-83,071,896 (from NCBI)

▼ Cloning and Expression
Chen et al. (1996) isolated a cDNA encoding RAB30, a small GTP-binding protein of the RAB family, from a human melanocyte cDNA library and from melanoma cells. The deduced 203-amino acid RAB30 protein shares minimal homology with previously documented GTPases. Northern blot analysis detected RAB30 transcripts ranging from 1.7 to 11 kb in most tissues tested.

▼ Mapping
By somatic cell hybrid analysis, Chen et al. (1996) mapped the RAB30 gene to chromosome 11. Scott (2001) localized the RAB30 gene to 11q12-q14 based on sequence similarity between the RAB30 sequence (GenBank U57092) and chromosome 11 clones (GenBank AP000893 and AP000905).

Tags: 11q14.1