THAP DOMAIN-CONTAINING PROTEIN 8; THAP8

HGNC Approved Gene Symbol: THAP8

Cytogenetic location: 19q13.12 Genomic coordinates (GRCh38): 19:36,034,983-36,054,761 (from NCBI)

▼ Cloning and Expression
By searching databases, Roussigne et al. (2003) identified several proteins containing an N-terminal THAP domain, including THAP8. The THAP domain of the deduced 274-amino acid THAP8 protein includes a C2CH signature, an AVPTIF box, and several other conserved amino acids.

▼ Mapping
Hartz (2009) mapped the THAP8 gene to chromosome 19q13.12 based on an alignment of the THAP8 sequence (GenBank AK057453) with the genomic sequence (build 36.1).