MITOCHONDRIAL RIBOSOMAL PROTEIN L37; MRPL37

HGNC Approved Gene Symbol: MRPL37

Cytogenetic location: 1p32.3 Genomic coordinates (GRCh38): 1:54,200,166-54,225,488 (from NCBI)

▼ Description
Mitochondria have their own translation system for production of 13 proteins essential for oxidative phosphorylation. MRPL37 is 1 of more than 70 protein components of mitochondrial ribosomes that are encoded by the nuclear genome (Kenmochi et al., 2001).

▼ Cloning and Expression
By searching databases using bovine Mrpl37 as query, followed by PCR of human genomic DNA, Kenmochi et al. (2001) cloned MRPL37.

▼ Mapping
By radiation hybrid analysis and analysis of an integrated BAC-STS map, Kenmochi et al. (2001) mapped the MRPL37 gene to chromosome 1p32.1.