Alternative titles; symbolsPCAF-ASSOCIATED FACTOR 65 ALPHA; PAF65APCAF-ASSOCIATED FACTOR, 65-KDHGNC Approved Gene Symbol: TAF6LCytogenetic location: 11q12.3 ...
Alternative titles; symbols
HGNC Approved Gene Symbol: TAF6L
Cytogenetic location: 11q12.3 Genomic coordinates (GRCh38): 11:62,771,395-62,787,341 (from NCBI)
▼ Cloning and Expression
Ogryzko et al. (1998) identified the human polypeptide PAF65A as a subunit of the PCAF complex (see 602303). PAF65A shows sequence similarity to human TAFII80 (602955). The predicted 622-amino acid protein contains a histone H4-like region (residues 12-86).
▼ Gene Function
Struhl and Moqtaderi (1998) reviewed the potential roles of the PCAF complex in transcription.
Hartz (2009) mapped the TAF6L gene to chromosome 11q12.3 based on an alignment of the TAF6L sequence (GenBank AF069735) with the genomic sequence (GRCh37).