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ZRSR2 PSEUDOGENE 1; ZRSR2P1

ZRSR2 PSEUDOGENE 1; ZRSR2P1

Alternative titles; symbolsZINC FINGER-, CCCH DOMAIN-, AND RNA-BINDING MOTIF-CONTAINING SERINE/ARGININE-RICH PROTEIN 1; ZRSR1U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A...

Alternative titles; symbols

  • ZINC FINGER-, CCCH DOMAIN-, AND RNA-BINDING MOTIF-CONTAINING SERINE/ARGININE-RICH PROTEIN 1; ZRSR1
  • U2 SMALL NUCLEAR RIBONUCLEOPROTEIN AUXILIARY FACTOR, SMALL SUBUNIT 1; U2AF1RS1

HGNC Approved Gene Symbol: ZRSR2P1

Cytogenetic location: 5q22 Genomic coordinates (GRCh38): 5:113,800,000-115,900,000

▼ Cloning and Expression
Hatada et al. (1991) isolated the imprinted mouse gene U2af1rs1 by restriction landmark genomic scanning. This gene is related to the human ribonucleoprotein auxiliary factor (191317) required for RNA splicing.

Kitagawa et al. (1995) isolated 3 human homologs of mouse U2af1rs1. The predicted 479-amino acid U2AF1RS1 protein is 92.1% identical to U2AF1RS2 (300028) and 78.8% identical to the mouse U2af1rs1 protein. In their Table 1, Kitagawa et al. (1995) presented DNA sequence analysis data which revealed higher similarity between the human U2AF1RS1 and U2AF1RS2 genes (94.6%) than that observed between the 2 mouse homologs (76.7%). See also 601080, the human locus they designated U2AF1RS3.

▼ Mapping
Kitagawa et al. (1995) mapped the ZRSR1 gene to chromosome 5q22 by fluorescence in situ hybridization.

Tags: 5q22

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