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NEUROBLASTOMA BREAKPOINT FAMILY, MEMBER 3; NBPF3

NEUROBLASTOMA BREAKPOINT FAMILY, MEMBER 3; NBPF3

HGNC Approved Gene Symbol: NBPF3Cytogenetic location: 1p36.12 Genomic coordinates (GRCh38): 1:21,436,774-21,484,899 (from NCBI)▼ TEXTFor background informati...

HGNC Approved Gene Symbol: NBPF3

Cytogenetic location: 1p36.12 Genomic coordinates (GRCh38): 1:21,436,774-21,484,899 (from NCBI)

▼ TEXT
For background information on the NBPF gene family, see NBPF1 (610501).

▼ Cloning and Expression
By searching EST databases for NBPF family members, Vandepoele et al. (2005) identified NBPF3. EST database analysis suggested ubiquitous NBPF3 expression.

▼ Gene Structure
Vandepoele et al. (2005) determined that the NBPF3 gene contains 13 coding exons.

Vandepoele and van Roy (2007) found that, unlike other transcriptionally active NBPF family members, NBPF3 lacks an insertion of a human endogenous retrovirus K long-terminal repeat in its 5-prime UTR.

▼ Mapping
By genomic sequence analysis and FISH, Vandepoele et al. (2005) mapped the NBPF3 gene to chromosome 1p36, where it lies in a cluster with NBPF1 and a pseudogene, NBPF2P.

Tags: 1p36.12