UBIQUINOL-CYTOCHROME C REDUCTASE, COMPLEX III SUBUNIT X; UQCR10

Alternative titles; symbols

• UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX, 7.2-KD SUBUNIT; UCRC
• CYTOCHROME C1-ASSOCIATED PROTEIN

HGNC Approved Gene Symbol: UQCR10

Cytogenetic location: 22q12.2 Genomic coordinates (GRCh38): 22:29,767,368-29,770,412 (from NCBI)

▼ Description
UCRC is a subunit of mitochondrial complex III (ubiquinol-cytochrome c reductase; EC 1.10.2.2), which forms the middle segment of the respiratory chain of the inner mitochondrial membrane (Schagger et al., 1995).

▼ Cloning and Expression
Schagger et al. (1995) isolated the 7.2-kD subunit of bovine and human mitochondrial complex III, which they called cytochrome C1 (CYC1; 123980)-associated protein.

▼ Mapping
The International Radiation Hybrid Mapping Consortium mapped the UCRC gene to chromosome 22 (STS-AA025006).